Anti-Progesterone Receptor Antibody
This mAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa) . Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P06401
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for this anti-Progesterone Receptor antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SPM566
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the anti-Progesterone Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This anti-Progesterone Receptor antibody is available for research use only.
Storage Conditions
Store the anti-Progesterone Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Nuclear, cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human breast carcinoma stained with anti-Progesterone Receptor antibody (clone SPM566) .
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