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IgG Antibody

Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with IgA, IgM, IgE, or IgD, heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P01857, P01859, P01860, P01861

Host

Mouse

Reactivity

Human

Immunogen

Purified human Ig Gamma Chain was used as the immunogen for this IgG antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

SPM556

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the IgG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This IgG antibody is available for research use only.

Storage Conditions

Store the IgG antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Location

Cytoplasm, Cell Surface and Secreted

Image Legend

IHC: Formalin-fixed, paraffin-embedded human tonsil stained with IgG antibody (SPM556)

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