Anti-MART-1 Antibody
Melan-A/MART-1 is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This mAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Product Specifications
Specifications
UniProt
Q16655
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for this anti-MART-1 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
SPM540
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the anti-MART-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This anti-MART-1 antibody is available for research use only.
Storage Conditions
Store the anti-MART-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/anti-mart-1-antibody-spm540-v9018
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
CAS Number
9007-83-4
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human melanoma stained with anti-MART-1 antibody (SPM540) .
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