Secretory Component Antibody / ECM1
This mAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q16610
Host
Mouse
Reactivity
Human
Immunogen
Secretory Component protein isolated from human colostrum was used as the immunogen for this Secretory Component antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SPM217
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the Secretory Component antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Secretory Component antibody is available for research use only.
Storage Conditions
Store the Secretory Component antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cell surface and cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human colon carcinoma stained with IgA Secretory Component antibody (SPM217) .
Documents
Frequently Asked Questions
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