RBMS2 Antibody / SCR3
RBMS2 is a member of a small family of proteins that bind single stranded DNA or RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, and are required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. RBMS2 (RNA-binding motif, single-stranded-interacting protein 2) is a 407 amino acid protein that contains 2 RRM (RNA recognition motif) domains and localizes to nucleus. It has been suggested that RBMS2 suppresses Cdc2 kinase and Cdc13 cyclin mutants through the induction of translation of Cdc2. The RBMS2 gene is conserved in chimpanzee, canine, bovine, mouse, rat and zebrafish, and maps to human chromosome 12q13.3.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
Q15434
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human RBMS2 protein was used as the immunogen for the RBMS2 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
PCRP-RBMS2-1B6
Applications
ELISA, IP, FACS
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the RBMS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RBMS2 antibody is available for research use only.
Storage Conditions
Aliquot the RBMS2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the RBMS2 antibody should be determined by the researcher.
Location
Nucleus, Cytoplasm
Image Legend
FACS staining of PFA-fixed human HeLa cells with RBMS2 antibody (blue, clone PCRP-RBMS2-1B6) and isotype control (red) .
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