Recombinant AKR1B1 Antibody / Aldose reductase
AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-4 µg/mL
UniProt
P15121
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human full-length AKR1B1 protein was used as the immunogen for the recombinant AKR1B1 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
AKR1B1/7009R
Type
Recombinant
Applications
WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the recombinant AKR1B1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant AKR1B1 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant AKR1B1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant AKR1B1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Frequently Asked Questions
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