What is the catalog number for ERG Antibody / Transcriptional regulator ERG?

The catalog number for ERG Antibody / Transcriptional regulator ERG is V8982-100UG.

What sizes are available for ERG Antibody / Transcriptional regulator ERG?

ERG Antibody / Transcriptional regulator ERG is available in the following size(s): 100 µg.

Is ERG Antibody / Transcriptional regulator ERG in stock?

ERG Antibody / Transcriptional regulator ERG is currently made to order / not held in immediate stock. Contact us for lead time.

ERG Antibody / Transcriptional regulator ERG

The transcription factor erythroblastosis virus E26 transforming sequence related gene (ERG) functions as a regulator of key cellular functions to promote endothelial homeostasis. Expression of ERG has been observed in both benign and malignant vascular endothelial tumors, such as hemangiomas and Kaposi sarcomas, respectively. Carcinomas of the breast, colon, and urothelium have demonstrated absence of ERG expression, whereas presence of the protein has been confirmed in a subset of prostate carcinoma cases. Anti-ERG can be a useful tool for identifying vascular endothelial neoplasms and distinguishing prostate carcinoma from epithelial tumors of non-prostatic origin.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P11308

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human full-length ERG protein was used as the immunogen for the ERG antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

ERG/2107

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the ERG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ERG antibody is available for research use only.

Storage Conditions

Aliquot the ERG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the ERG antibody should be determined by the researcher.

Location

Nucleus, cytoplasm

Image Legend

Analysis of HuProt (TM) microarray containing more than 19,000 full-length human proteins using ERG antibody (clone ERG/2107) . These results demonstrate the foremost specificity of the ERG/2107 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.