IL3RA Antibody / CD123
CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5) . The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA: 2-4 µg/mL (order BSA-free format for coating)
UniProt
P26951
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 26-171 was used as the immunogen for the IL3RA antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
IL3RA/2065
Applications
ELISA
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the IL3RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IL3RA antibody is available for research use only.
Storage Conditions
Aliquot the IL3RA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the IL3RA antibody should be determined by the researcher.
Location
Cell surface and cytoplasm
Image Legend
Frequently Asked Questions
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