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CD79b Antibody

The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.

Product Specifications

CAS Number

9000-83-3

Specifications

ELISA: 2-4 µg/mL (order BSA-azide free format for coating)

UniProt

P40259

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 29-159 was used as the immunogen for the CD79b antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

IGB/2940R

Type

Recombinant

Applications

ELISA

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the CD79b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CD79b antibody is available for research use only.

Storage Conditions

Aliquot the CD79b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the CD79b antibody should be determined by the researcher.

Location

Cell surface

Image Legend

SDS-PAGE analysis of purified, BSA-free CD79b antibody (clone IGB/2940R) as confirmation of integrity and purity.

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