SOX9 Antibody
Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P48436
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 393-508 was used as the immunogen for the SOX9 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SOX9/2387
Applications
WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the SOX9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SOX9 antibody is available for research use only.
Storage Conditions
Aliquot the SOX9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the SOX9 antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Western blot testing of human PC3 cell lysate using SOX9 antibody (clone SOX9/2387) . Predicted molecular weight: 56-65 kDa.
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