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SOX9 Antibody

Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P48436

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 393-508 was used as the immunogen for the SOX9 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

SOX9/2387

Applications

WB, IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the SOX9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This SOX9 antibody is available for research use only.

Storage Conditions

Aliquot the SOX9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the SOX9 antibody should be determined by the researcher.

Location

Nucleus

Image Legend

Western blot testing of human PC3 cell lysate using SOX9 antibody (clone SOX9/2387) . Predicted molecular weight: 56-65 kDa.

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