Resistin Antibody / RETN

The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to Insulin) also known as ADSF, is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q9HD89

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 19-108 was used as the immunogen for the Resistin antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

RETN/3331

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the Resistin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Resistin antibody is available for research use only.

Storage Conditions

Aliquot the Resistin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Resistin antibody should be determined by the researcher.

Location

Secreted

Image Legend

IHC staining of FFPE human spleen tissue with Resistin antibody (clone RETN/3331) . Negative control inset: PBS used instead of primary antibody to control for secondary Ab binding. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.