Blood Group H2 Antibody / ABO
This antibody reacts with H type 2 blood group epitope Fuca1-2 Galb1-4 GlcNAc. It does not cross-react with human blood group H type 1, 3 or 4, nor with the closely related type 2 antigen Ley and Lex. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular trans- formation. Blood group related antigens are usually mucin-type and are detected on erythrocytes, certain epithelial cells and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A (1 and 2), B, H (1 and 2), M, N, Lewis A, Lewis B, Lewis X, Lewis Y and precursor type 1 chain antigens. The expressions of the H1 and H2 in different cell types are con- trolled by different genes.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 2-4 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P16442
Host
Mouse
Reactivity
Human
Immunogen
Clonality
Monoclonal
Isotype
IgA
Clone
A51-B/A6
Applications
IF, IHC-P
Purity
Protein affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Blood Group H2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Blood Group H2 antibody is available for research use only.
Storage Conditions
Aliquot the Blood Group H2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Blood Group H2 antibody should be determined by the researcher.
Location
Cell Surface
Documents
Frequently Asked Questions
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