Carbonic Anhydrase VIII Antibody / CA8

Carbonic anhydrase-related protein is an protein that in humans is encoded by the CA8 gene. The CA8 protein lacks the catalytic activity of other carbonic anhydrase enzymes. A rare, autosomal recessive form of cerebellar ataxia known as cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CAMRQ3) is caused by mutations in the CA8 gene. [Wiki]

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P35219

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human Carbonic Anhydrase VIII/CA8 protein was used as the immunogen for the Carbonic Anhydrase VIII antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

CA8/6572

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the Carbonic Anhydrase VIII antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Carbonic Anhydrase VIII antibody is available for research use only.

Storage Conditions

Aliquot the Carbonic Anhydrase VIII antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Carbonic Anhydrase VIII antibody should be determined by the researcher.

Location

Cytoplasm, Cell surface

Image Legend

IHC staining of FFPE human brain tissue with Carbonic Anhydrase VIII antibody (clone CA8/6572) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.