Beta Amyloid Antibody
Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the /A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P05067
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 578-680 from the human protein was used as the immunogen for the Beta Amyloid antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
APP/3343
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Beta Amyloid antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Beta Amyloid antibody is available for research use only.
Storage Conditions
Store the Beta Amyloid antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Beta Amyloid antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Frequently Asked Questions
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