BAFF-R Antibody / BAFF Receptor
Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) ; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q96RJ3
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human CD268 protein was used as the immunogen for the BAFF-R antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
BAFFR/1558
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the BAFF-R antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This BAFF-R antibody is available for research use only.
Storage Conditions
Store the BAFF-R antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the BAFF-R antibody should be determined by the researcher.
Location
Cell surface
Image Legend
Frequently Asked Questions
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