Periostin Antibody / POSTN

Periostin (PN, POSTN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for 1) . Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

UniProt

Q15063

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the Periostin antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

POSTN/3503

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the Periostin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Periostin antibody is available for research use only.

Storage Conditions

Store the Periostin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the Periostin antibody should be determined by the researcher.

Location

Secreted, cytoplasm

Image Legend

IHC staining of FFPE human colon carcinoma with Periostin antibody (clone POSTN/3503) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.