Recombinant Podoplanin Antibody
It recognizes a muco-protein of 38-43kDa, which is identified as Podoplanin (PDPN) . It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
Product Specifications
CAS Number
9000-83-3
Specifications
ELISA (order Ab without BSA for coating), Western blot: 2-4 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q86YL7
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1-100 from the human protein was used as the immunogen for the recombinant Podoplanin antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
PDPN/4009R
Type
Recombinant
Applications
ELISA, WB, IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant Podoplanin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant Podoplanin antibody is available for research use only.
Storage Conditions
Store the recombinant Podoplanin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant Podoplanin antibody should be determined by the researcher.
Location
Cell surface, cytoplasmic
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Neisseria Gonorrhoeae groS Protein (aa 1-96) (strain ATCC 700825 / FA 1090)
DZIP3 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Myeloperoxidase (MPO) Mouse Monoclonal Antibody [Clone ID: LBI6A9]
