ITLN1 Antibody / Intelectin 1

Human intelectin-1 (ITLN-1) is a novel identified galactose binding lectin that is usually expressed in the heart, small intestine, and colon. In normal tissues, human intelectin-1 was mainly secreted from gastrointestinal goblet cells along with mucus into the intestinal lumen, and it was also expressed, to a lesser extent, in mesothelial cells and urinary epithelial cells. It is overexpressed in human malignant pleural mesothelioma (MPM) . In contrast, sarcomatoid-type MPMs, biphasic MPMs, and poorly differentiated MPMs are rarely positive for intelectin-1, and it is not expressed in other cancers, except in mucus-producing adenocarcinoma.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

UniProt

Q8WWA0

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 16-141 from the human protein was used as the immunogen for the ITLN1 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

ITLN1/4064

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the ITLN1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This ITLN1 antibody is available for research use only.

Storage Conditions

Store the ITLN1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the ITLN1 antibody should be determined by the researcher.

Location

Cytoplasm, cell membrane, secreted

Image Legend

IHC staining of FFPE human colon with ITLN1 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.