Intelectin 1 Antibody

Human intelectin-1 (ITLN-1) is a novel identified galactose binding lectin that is usually expressed in the heart, small intestine, and colon. In normal tissues, human intelectin-1 was mainly secreted from gastrointestinal goblet cells along with mucus into the intestinal lumen, and it was also expressed, to a lesser extent, in mesothelial cells and urinary epithelial cells. It is overexpressed in human malignant pleural mesothelioma (MPM) . In contrast, sarcomatoid-type MPMs, biphasic MPMs, and poorly differentiated MPMs are rarely positive for intelectin-1, and it is not expressed in other cancers, except in mucus-producing adenocarcinoma.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

UniProt

Q8WWA0

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 16-141 from the human protein was used as the immunogen for the Intelectin 1 antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

ITLN1/4062

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the Intelectin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Intelectin 1 antibody is available for research use only.

Storage Conditions

Store the Intelectin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the Intelectin 1 antibody should be determined by the researcher.

Location

Cytoplasm, cell membrane, secreted

Image Legend

IHC staining of FFPE human colon with Intelectin 1 antibody (clone ITLN1/4062) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.