Recombinant Type I Cytokeratin Antibody (CK10/14/15/16/19)
The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q7Z794
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 100-200 from Type I Cytokeratins was used as the immunogen for the recombinant Type I Cytokeratin antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
KRTL/4440R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant Type I Cytokeratin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant Type I Cytokeratin antibody is available for research use only.
Storage Conditions
Store the recombinant Type I Cytokeratin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant Type I Cytokeratin antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Documents
Frequently Asked Questions
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