Gedunin
Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research[3].
Product Specifications
CAS Number
2753-30-2
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
HSP
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gedunin.html
Purity
98.59
Solubility
DMSO : 48.26 mg/mL (ultrasonic)
Smiles
O=C1[C@](O2)([H])[C@@]32[C@](CC[C@]4([H])[C@@]5(C)C=CC(C(C)(C)[C@]5([H])C[C@@H](OC(C)=O)[C@]43C)=O)(C)[C@H](C6=COC=C6)O1
Molecular Formula
C28H34O7
Molecular Weight
482.57
Precautions
H302, H312, H332
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HSP90
Available Sizes
Frequently Asked Questions
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