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Integrin alpha V + beta 6 Antibody

Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunoprecipitation: 1-2ug/500ug protein, Flow cytometry: 0.5-1ug/million cells, Immunofluorescence: 1-2 µg/mL, Western blot: 0.5-1 µg/mL

UniProt

P06756; P18564

Host

Rat

Reactivity

Human

Immunogen

Mouse fibroblasts retrovirally infected with cDNA to express a mouse/human avb6 chimera was used as the immunogen for the Integrin alpha V + beta 6 antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

AvB6 53a.2

Applications

IP, FACS, IF, WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the Integrin alpha V + beta 6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Integrin alpha V + beta 6 antibody is available for research use only.

Storage Conditions

Store the Integrin alpha V + beta 6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the Integrin alpha V + beta 6 antibody should be determined by the researcher.

Location

Membrane

Image Legend

SDS-PAGE analysis of purified, BSA-free Integrin alpha V + beta 6 antibody (clone AvB6 53a.2) as confirmation of integrity and purity.

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