Elastin Antibody
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA: order Ab without BSA for coating, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P15502
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human Elastin protein was used as the immunogen for the Elastin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
ELN/2069
Applications
ELISA, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Elastin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Elastin antibody is available for research use only.
Storage Conditions
Store the Elastin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Elastin antibody should be determined by the researcher.
Location
Secreted
Image Legend
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