Recombinant PSA Antibody / Prostate Specific Antigen
Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA) . This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT) . A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This mAb makes an excellent pair with clone 1A7G6B6 for PSA tests.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P07288
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant full-length human KLK3/PSA protein was used as the immunogen for the recombinant PSA antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
KLK3/4551R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant PSA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant PSA antibody is available for research use only.
Storage Conditions
Store the recombinant PSA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/recombinant-psa-antibody-prostate-specific-antigen-klk34551r-v8460
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant PSA antibody should be determined by the researcher.
CAS Number
9000-83-3
Location
Cytoplasmic
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