FGF21 Antibody / Fibroblast Growth Factor 21
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q9NSA1
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 91-209 from the human protein was used as the immunogen for the FGF21 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
FGF21/3691
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the FGF21 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This FGF21 antibody is available for research use only.
Storage Conditions
Store the FGF21 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the FGF21 antibody should be determined by the researcher.
Location
Secreted (extracellular)
Image Legend
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
