Recombinant Mammaglobin Antibody / SCGB2A2

Mammaglobin, a 10 kDa protein, is a cytoplasmic mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

UniProt

Q13296

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant full-length human Mammaglobin/SCGB2A2 protein was used as the immunogen for the recombinant Mammaglobin antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

MGB/4058R

Type

Recombinant

Applications

IHC-P

Purity

Protein A affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the recombinant Mammaglobin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant Mammaglobin antibody is available for research use only.

Storage Conditions

Store the recombinant Mammaglobin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the recombinant Mammaglobin antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human breast carcinoma with recombinant Mammaglobin antibody (clone MGB/4058R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.