FLI1 Antibody
Recognizes a protein of 51kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90% of Ewings Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.
Product Specifications
UniProt
Q01543
Host
Mouse
Immunogen
A portion of amino acids 107-261 from the human protein was used as the immunogen for the FLI1 antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Applications
ELISA
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the FLI1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This FLI1 antibody is available for research use only.
CAS Number
9007-83-4
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