Aciculin Antibody / PGM5 / Phosphoglucomutase 5
Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q15124
Host
Mouse
Reactivity
Human
Immunogen
The cytoskeletal fraction of the human myometrium tissue extract was used as the immunogen for the Aciculin antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
14F8/F8
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Aciculin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Aciculin antibody is available for research use only.
Storage Conditions
Store the Aciculin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Aciculin antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Frequently Asked Questions
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