Recombinant ATRX Antibody
ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 thalassemia or ATRX syndrome
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P46100
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human ATRX protein was used as the immunogen for the recombinant ATRX antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RATRX/3446
Type
Recombinant
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant ATRX antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant ATRX antibody is available for research use only.
Storage Conditions
Store the recombinant ATRX antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/recombinant-atrx-antibody-ratrx3446-v8409
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant ATRX antibody should be determined by the researcher.
CAS Number
9000-83-3
Location
Nuclear
Image Legend
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
ERCC6 Antibody - C-terminal region : FITC (ARP37966_P050-FITC)