TdT Antibody / DNA nucleotidylexotransferase
Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3 termini of DNA. The human TdT gene maps to chromosome 10q24.1 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. It is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA: 2-4 µg/mL for coating; order Ab without BSA, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P04053
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 52-192 from the human protein was used as the immunogen for the TdT antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
TDT/1393
Applications
ELISA, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the TdT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TdT antibody is available for research use only.
Storage Conditions
Store the TdT antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the TdT antibody should be determined by the researcher.
Location
Nucleus
Image Legend
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