Recombinant CD162 Antibody
CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
Product Specifications
CAS Number
9000-83-3
Specifications
ELISA: order Ab without BSA for coating
UniProt
Q14242
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human CD162 protein was used as the immunogen for the recombinant CD162 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RPSGL1/1601
Type
Recombinant
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant CD162 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant CD162 antibody is available for research use only.
Storage Conditions
Store the recombinant CD162 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant CD162 antibody should be determined by the researcher.
Location
Cell surface
Image Legend
SDS-PAGE analysis of purified, BSA-free recombinant CD162 antibody (clone rPSGL1/1601) as confirmation of integrity and purity.
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