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Recombinant TLR2 Antibody

This MAb reacts with human Toll-like receptor 2 (TLR2) . It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Product Specifications

CAS Number

9000-83-3

Specifications

ELISA: For coating order antibody without BSA

UniProt

O60603

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant full-length human TLR2 protein was used as the immunogen for the recombinant TLR2 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

TLR2/3894R

Type

Recombinant

Applications

ELISA

Purity

Protein A affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the recombinant TLR2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant TLR2 antibody is available for research use only.

Storage Conditions

Store the recombinant TLR2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the recombinant TLR2 antibody should be determined by the researcher.

Location

Cell surface

Image Legend

SDS-PAGE analysis of purified, BSA-free recombinant TLR2 antibody (clone TLR2/3894R) as confirmation of integrity and purity.

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