Recombinant TLR2 Antibody
This MAb reacts with human Toll-like receptor 2 (TLR2) . It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Product Specifications
CAS Number
9000-83-3
Specifications
ELISA: order Ab without BSA for coating
UniProt
O60603
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human TLR2 protein was used as the immunogen for the recombinant TLR2 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RTLR2/221
Type
Recombinant
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant TLR2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant TLR2 antibody is available for research use only.
Storage Conditions
Store the recombinant TLR2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant TLR2 antibody should be determined by the researcher.
Location
Cell surface
Image Legend
SDS-PAGE analysis of purified, BSA-free recombinant TLR2 antibody (clone rTLR2/221) as confirmation of integrity and purity.
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