INHA Antibody / Inhibin alpha

It recognizes a 47kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH) . Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

UniProt

P05111

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 233-362 from the human protein was used as the immunogen for the INHA antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

INHA/1168

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the INHA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This INHA antibody is available for research use only.

Storage Conditions

Store the INHA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the INHA antibody should be determined by the researcher.

Location

Nuclear and Cytoplasmic (secreted)

Image Legend

IHC staining of FFPE human testicular carcinoma with INHA antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.