INHA Antibody / Inhibin alpha
It recognizes a 47kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH) . Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P05111
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 233-362 from the human protein was used as the immunogen for the INHA antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
INHA/1168
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the INHA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This INHA antibody is available for research use only.
Storage Conditions
Store the INHA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the INHA antibody should be determined by the researcher.
Location
Nuclear and Cytoplasmic (secreted)
Image Legend
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