FN1 Antibody / Fibronectin
Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order Ab without BSA for coating), Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P02751
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 467-595 from the human protein was used as the immunogen for the FN1 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
FN1/2948
Applications
ELISA, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the FN1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This FN1 antibody is available for research use only.
Storage Conditions
Store the FN1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the FN1 antibody should be determined by the researcher.
Location
Connective tissue matrix
Image Legend
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
