BCL10 Antibody
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t (1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14 translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Product Specifications
CAS Number
9000-83-3
Specifications
Flow cytometry: 1-2ug/million cells, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
O95999
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 122-168 from the human protein were used as the immunogen for the BCL10 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RBL10/411
Type
Recombinant
Applications
FACS, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the BCL10 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This BCL10 antibody is available for research use only.
Storage Conditions
Store the BCL10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the BCL10 antibody should be determined by the researcher.
Location
Nuclear and cytoplasmic
Image Legend
Flow cytometry testing of PFA-fixed human K562 cells with BCL10 antibody (clone rBL10/411) ; Red=isotype control, Blue= BCL10 antibody.
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Frequently Asked Questions
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