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CD5L Antibody

CD5L (CD5 molecule-like), also known as API6, PRO229, Sp or SP-ALPHA, is a 347 amino acid secreted protein that belongs to the scavenger receptor cysteine-rich (SRCR) family of leukocyte regulating proteins. Expressed in bone marrow, spleen, thymus, lymph node and fetal liver, CD5L is thought to be involved in regulating the immune system via binding to peripheral monocytes and mediating their activation and overall survival. CD5L has three cysteine-rich domains and, in addition to its role in the immune system, may function to inhibit apoptosis and promote macrophage survival.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

UniProt

O43866

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 269-366 from the human protein was used as the immunogen for the CD5L antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

CD5L/2991

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the CD5L antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CD5L antibody is available for research use only.

Storage Conditions

Store the CD5L antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Product Datasheet

https://www.nsjbio.com/tds-pdf/cd5l-antibody-cd5l2991-v8377

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the CD5L antibody should be determined by the researcher.

Location

Secreted

Image Legend

IHC staining of FFPE human tonsil with CD5L antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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