IL-10RA Antibody / IL-10R1
This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/10^6 cells
UniProt
Q61727
Host
Rat
Reactivity
Mouse
Immunogen
Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
1B1.3a
Applications
FACS
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the IL-10RA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This IL-10RA antibody is available for research use only.
Storage Conditions
Store the IL-10RA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the IL-10RA antibody should be determined by the researcher.
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