HHV8 Antibody / Herpes Virus 8
HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1-3 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
Host
Rat
Reactivity
HSV-1
Immunogen
Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8 was used as the immunogen for this HHV8 antibody.
Clonality
Monoclonal
Isotype
IgG2c κ
Clone
LN53
Applications
ELISA, IF, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the human HHV8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This HHV8 antibody is available for research use only.
Storage Conditions
Store the human HHV8 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the human HHV8 antibody should be determined by the researcher.
Image Legend
SDS-PAGE analysis of purified, BSA-free HHV8 antibody (clone LN53) as confirmation of integrity and purity.
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