CD79b Antibody
CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
Product Specifications
UniProt
P40259
Host
Mouse
Immunogen
The C-terminal portion of the human protein was used as the immunogen for this CD79b antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
WB, IHC-P
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the CD79b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD79b antibody is available for research use only.
CAS Number
9007-83-4
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