Recombinant ATG5 Antibody
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy; a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.
Product Specifications
CAS Number
9000-83-3
Specifications
ELISA: order Ab without BSA for coating
UniProt
Q9H1Y0
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1-119 from the human protein was used as the immunogen for the recombinant ATG5 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
AGT5/3220R
Type
Recombinant
Applications
ELISA
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant ATG5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant ATG5 antibody is available for research use only.
Storage Conditions
Store the recombinant ATG5 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant ATG5 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
SDS-PAGE analysis of purified, BSA-free recombinant ATG5 antibody (clone AGT5/3220R) as confirmation of integrity and purity.
Documents
Frequently Asked Questions
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