TNFRSF18 Antibody / GITR
The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals through protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating & Azide)
UniProt
Q9Y5U5
Host
Mouse
Reactivity
Human
Immunogen
Human full-length TNFRSF18 protein was used as the immunogen for this TNFRSF18 antibody.
Clonality
Monoclonal
Isotype
IgG3 κ
Clone
GITR/1585
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the TNFRSF18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TNFRSF18 antibody is available for research use only.
Storage Conditions
Store the TNFRSF18 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the TNFRSF18 antibody should be determined by the researcher.
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