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Recombinant VLDL Receptor Antibody / VLDLR

VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF) -like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Product Specifications

CAS Number

9000-83-3

Specifications

ELISA (order BSA-free format for coating)

UniProt

P98155

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant protein fragment from the C-terminal region of VLDLR was used as the immunogen for this recombinant VLDL Receptor antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

VLDLR/2896R

Type

Recombinant

Applications

ELISA

Purity

Protein A affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the recombinant VLDL Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant VLDL Receptor antibody is available for research use only.

Storage Conditions

Store the recombinant VLDL Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the recombinant VLDL Receptor antibody should be determined by the researcher.

Image Legend

SDS-PAGE analysis of purified, BSA-free recombinant VLDL Receptor antibody (clone VLDLR/2896R) as confirmation of integrity and purity.

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