Recombinant VLDL Receptor Antibody / VLDLR
VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF) -like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
Product Specifications
CAS Number
9000-83-3
Specifications
ELISA (order BSA-free format for coating)
UniProt
P98155
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant protein fragment from the C-terminal region of VLDLR was used as the immunogen for this recombinant VLDL Receptor antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
VLDLR/2896R
Type
Recombinant
Applications
ELISA
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant VLDL Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant VLDL Receptor antibody is available for research use only.
Storage Conditions
Store the recombinant VLDL Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant VLDL Receptor antibody should be determined by the researcher.
Image Legend
SDS-PAGE analysis of purified, BSA-free recombinant VLDL Receptor antibody (clone VLDLR/2896R) as confirmation of integrity and purity.
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