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VEGF Antibody

This mAb recognizes proteins of 19-22kDa (reducing) and 38kDa-44kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet-derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

Product Specifications

UniProt

P15692

Host

Mouse

Immunogen

Recombinant human protein was used as the immunogen for the VEGF antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Applications

ELISA, IHC-P

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the VEGF antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This VEGF antibody is available for research use only.

CAS Number

9007-83-4

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