Recombinant GRP94 Antibody / HSP90B1
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96) . Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90) . This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp's are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
Product Specifications
CAS Number
9000-83-3
Specifications
Flow cytometry: 1-2ug/10^6 cells, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P14625
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant full-length human protein was used as the immunogen for this recombinant GRP94 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
HSP90B1/3168R
Type
Recombinant
Applications
FACS, IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant GRP94 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant GRP94 antibody is available for research use only.
Storage Conditions
Store the recombinant GRP94 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant GRP94 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
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