C1QA Antibody / Complement C1q A-Chain

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P02745

Host

Mouse

Reactivity

Human

Immunogen

Amino acids 104-237 were used as the immunogen for the C1QA antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

CCSA-1

Applications

WB, IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the C1QA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This C1QA antibody is available for research use only.

Storage Conditions

Store the C1QA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the C1QA antibody may be required due to differences in protocols and secondary/substrate sensitivity.