MS152
MS152 is an oral bioactive inhibitor of EHMT2/G9a. MS152 reactivats maternally silenced Prader-Willi syndrome (PWS) genes in brain and liver tissues of PWS mouse models[1].
Product Specifications
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ms152.html
Concentration
10mM
Purity
99.36
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=CC2=C(C=C1OCCCN3CCCC3)N=C(N)C=C2C4CCOCC4
Molecular Formula
C22H31N3O3
Molecular Weight
385.50
References & Citations
[1]Sung Eun Wang, et al. Newly developed oral bioavailable EHMT2 inhibitor as a potential epigenetic therapy for Prader-Willi syndrome. Mol Ther. 2024 May 24:S1525-0016 (24) 00336-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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