TFF2 Antibody / Trefoil factor 2
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA/azide-free format for coating)
UniProt
Q03403
Host
Mouse
Reactivity
Human
Immunogen
Clonality
Monoclonal
Isotype
IgM k
Clone
GE16C
Applications
ELISA
Purity
PEG precipitation
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the TFF2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TFF2 antibody is available for research use only.
Storage Conditions
Store the TFF2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the TFF2 antibody should be determined by the researcher.
Frequently Asked Questions
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